Blakiston is a surname. Notable people with the surname include:
- Arthur Frederick Blakiston (1892-1974), English Rugby Union player and First World War officer
- Bob Blakiston (1855-1918), American Major League Baseball outfielder
- Caroline Blakiston (1933-), English actress
- Charles Blakiston (1825–1898), New Zealand politician
- Herbert Edward Douglas Blakiston (1862–1942), President of Trinity College, Oxford, Vice-Chancellor of Oxford University
- John Blakiston (1603–1649), English MP, coal merchant and one of the regicides of King Charles I
- John Blakiston-Houston (1829-1920), Irish member of parliament
- Matthew Blakiston (1702–1774), Lord Mayor of London, 1st Baronet of London
- Nathaniel Blakiston (died 1722), Royal Governor of the Maryland colony from 1698 to 1702
- Nehemiah Blakiston, Royal Governor of the Maryland colony from 1691 to 1692
- Oswell Blakeston, pseudonym of Henry Joseph Hasslacher (1907–1985), writer, artist and poet
- Thomas Blakiston (1832-1891), English explorer and naturalist
See also
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