• 18 January - A Delta IV Heavy launches the classified USA-202 spy satellite.
• 23 January - An H-IIA launches the GOSAT, Sohla-1, Sprite-Sat, SDS-1, Kagayaki, PRISM, STARS and KKS-1 satellites
• 30 January - The Tsyklon-3 makes its final flight, launching the Koronas-Foton satellite.
• 2 February - Iran conducts its first orbital launch, with a Safir launching the Omid satellite.
• 6 February - A Delta II 7320-10C launches the NOAA-19 weather satellite.
• 10 February - A Soyuz-U launches Progress M-66 spacecraft to resupply the ISS.
• 10 February - Kosmos 2251 collides with Iridium 33, resulting in the destruction of both satellites.
• 11 February - A Proton-M/Briz-M launches the Express-AM44 and -MD1 satellites.
• 12 February - An Ariane 5 launches the Hot Bird 10, and NSS-9 communication satellites, and two Spirale satellites.
• 24 February - A Taurus-XL fails to launch OCO due to a payload fairing malfunction.
• 26 February - A Zenit-3SLB launches the Telstar 11N communications satellite.
• 28 February - A Proton-K/DM-2 launches the Raduga-1 communications satellite.
• 1 March - Chang'e 1 is deorbited and impacts the Moon, completing a successful 16-month mission.
• 7 March - A Delta II 7925-10L launches the Kepler space photometer.
• 15 March - Space Shuttle Discovery launches on mission STS-119 to deliver the S6 truss to the International Space Station.
• 17 March - A Rokot/Briz-KM launches the Gravity Field and Steady-State Ocean Circulation Explorer.
• 24 March - A Delta II 7925-9.5 launches the GPS IIR-20 satellite.
• 26 March - A Soyuz-FG launches Soyuz TMA-14 with the Expedition 19 crew of the ISS and the first repeat spaceflight participant.
• 3 April - A Proton-M/Briz-M launches the Eutelsat W2A satellite.
• 4 April - An Atlas V launches the WGS-2 satellite.
• 14 May - An Ariane 5ECA launches the Herschel and Planck space telescopes
• 6 July - A Rokot launches three satellites for the Russian government
• 14 July - A Falcon 1 launches the RazakSAT satellite

This list is out of date.

• 29 July - A Dnepr-1 launches the DubaiSat-1, Deimos-1, UK-DMC 2, Nanosat 1B and AprizeSat-3 and 4 satellites
• 11 August - A Proton-M/Briz-M launches AsiaSat 5
• 17 August - A Delta II 7925-9.5 carries the final GPS IIR-M satellite, GPS IIR-21, into orbit.
• 21 August - An Ariane 5 ECA takes the JCSAT-12 and Optus D3 communications satellites to GTO.
• 25 August - The Russo-South Korean Naro-1 rocket makes its maiden flight, launching the STSAT-2 spacecraft, which fails to reach orbit.
• 29 August - Space Shuttle Discovery launches on mission STS-128.
• 31 August - A Long March 3B partially fails to launch Palapa-D to GTO.