Rhodope may refer to:
- Rhodope (mythology), a figure of Greek mythology
 - Rhodope Mountains, in Bulgaria and Greece
 - Rhodope (regional unit), of Greece
 - Rhodope (province), a Roman and Byzantine province
 - 166 Rhodope, an asteroid
 - Rhodope (genus), a genus of the family Rhodopidae, order Rhodopemorpha, class Gastropoda
 - Mylothris rhodope, a dotted border butterfly of tropical Africa commonly known as the Rhodope
 
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