Séamus Murphy may refer to:
- Seamus Murphy (1907–75) Irish sculptor
 - Séamus Murphy (Gaelic footballer) (born 1938) Kerry player
 - Séamus Murphy (Wexford hurler) (born 1950s) player and coach
 - Séamus Murphy (Carlow hurler) (born 1986)
 - Seamus Murphy, Irish filmmaker
 
See also
- James Murphy (disambiguation) anglicised spelling
 - Seamus McMurphy (1720–50) Irish poet and outlaw
 
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