Skopin (Russian: Скопин) is a Russian masculine surname, its feminine counterpart is Skopina. It may refer to the following notable people:
- Alexander Skopin (1927–2003), Russian mathematician
- Mikhail Skopin-Shuisky (1586–1610), Russian statesman and military figure
- Timofey Skopin (born 1989), Russian speed skater
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