Ōe, Oe or Ooe (written: 大江 lit. "large bay") is a Japanese surname. Notable people with the surname include:

• Princess Ōe (大江皇女, died 699), princess of ancient Japan
• Hikari Ōe (大江 光, born 1963), the son of Kenzaburō Ōe
• Senri Oe (大江 千里, born 1960), Japanese singer-songwriter
• Hideo Oe (大江 英雄, born 1944), Japanese rower
• Hikaru Ōe (大江 光, born 1995), Japanese snowboarder
• Kenzaburō Ōe (大江 健三郎, 1935–2023), Japanese novelist
• Momoe Oe (大江 百重, born 1980), Japanese professional wrestler
• Takamasa Oe (大江 崇允, born 1981), Japanese screenwriter
• Tatsuya Oe (オオエ タツヤ, born 1969), Japanese electronic musician known as Captain Funk