Singles
2016 Santiago Challenger
Champion	Máximo González
Runner-up	Rogério Dutra Silva
Score	6–2, 7–6(7–5)

Rogério Dutra Silva was the defending champion but lost in the final to Máximo González.

González won the title after defeating Dutra Silva 6–2, 7–6^(7–5) in the final.

Seeds

Draw

Finals

	Semifinals							Final
	1	Horacio Zeballos	1	77	67
		Máximo González	6	62	79
									Máximo González	6	77
								4	Rogério Dutra Silva	2	65
	4	Rogério Dutra Silva	5
	2	Thiago Monteiro	0r

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	H Zeballos	3	79	6
		C Garín	6	67	4			1	H Zeballos	6	6
	WC	N Jarry	65	3				LL	JP Sorgi	3	4
	LL	JP Sorgi	77	6											1	H Zeballos	77	6
		T Lipovšek Puches	5	6	3											P Sousa	65	4
		P Sousa	7	3	6				P Sousa	7	7
	PR	F de Paula	2	1				6	G Andreozzi	5	5
	6	G Andreozzi	6	6																		1	H Zeballos	1	77	67
	LL	F Mena	6	0	3																		M González	6	62	79
	Alt	M Linzer	4	6	6			Alt	M Linzer	3	4
	WC	J Munar	2	2					C Ruud	6	6
		C Ruud	6	6												C Ruud	7	5	3
		A Ghem	6	3	3											M González	5	7	6
		M González	2	6	6				M González	6	6
	WC	MT Barrios Vera	4	4				7	L Mayer	1	2
	7	L Mayer	6	6

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	8	N Kicker	6	6
		J Samper Montaña	4	3				8	N Kicker	6	2	2
		M Bourgue	7	6					M Bourgue	2	6	6
		J Hernández	5	1												M Bourgue	2	1
	WC	Bastián Malla	4	5											4	R Dutra Silva	6	6
		Maximiliano Estévez	6	7					M Estévez	63	6	4
	Q	A Collarini	65	6	2			4	R Dutra Silva	77	4	6
	4	R Dutra Silva	77	3	6																	4	R Dutra Silva	5
	5	J Souza	2	4																		2	T Monteiro	0r
		A Velotti	6	6					A Velotti	6	62	4
	Q	D Dutra da Silva	2	6	4				A Michon	3	77	6
		A Michon	6	4	6											A Michon	5	4
	Q	JP Paz	6	6											2	T Monteiro	7	6
	Q	JP Ficovich	1	3				Q	JP Paz	4	2
		JI Londero	5	67				2	T Monteiro	6	6
	2	T Monteiro	7	79

References

• Main draw
• Qualifying draw