CLGN
Identifiers
AliasesCLGN, calmegin
External IDsOMIM: 601858 MGI: 107472 HomoloGene: 68392 GeneCards: CLGN
Orthologs
SpeciesHumanMouse
Entrez

1047

12745

Ensembl

ENSG00000153132

ENSMUSG00000002190

UniProt

O14967

P52194

RefSeq (mRNA)

NM_001130675
NM_004362

NM_009904
NM_001329627
NM_001329680

RefSeq (protein)

NP_001124147
NP_004353

NP_001316556
NP_001316609
NP_034034

Location (UCSC)Chr 4: 140.39 – 140.43 MbChr 8: 84.12 – 84.16 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Calmegin, also known as CLGN, is a protein which in humans is encoded by the CLGN gene.[5] Calmegin is also present in other animals including mice.[6]

Function

Calmegin is a testis-specific endoplasmic reticulum chaperone protein. CLGN may play a role in spermatogeneisis and infertility.[5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000153132 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000002190 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: CLGN calmegin".
  6. Watanabe D, Yamada K, Nishina Y, Tajima Y, Koshimizu U, Nagata A, Nishimune Y (March 1994). "Molecular cloning of a novel Ca(2+)-binding protein (calmegin) specifically expressed during male meiotic germ cell development". J. Biol. Chem. 269 (10): 7744–7749. doi:10.1016/S0021-9258(17)37349-0. PMID 8126001.

Further reading

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