COL16A1
Identifiers
AliasesCOL16A1, 447AA, FP1572, collagen type XVI alpha 1, collagen type XVI alpha 1 chain
External IDsOMIM: 120326 MGI: 1095396 HomoloGene: 1397 GeneCards: COL16A1
Orthologs
SpeciesHumanMouse
Entrez

1307

107581

Ensembl

ENSG00000084636

ENSMUSG00000040690

UniProt

Q07092

Q8BLX7

RefSeq (mRNA)

NM_001856

NM_028266

RefSeq (protein)

NP_001847

NP_082542
NP_001391281
NP_001391282

Location (UCSC)Chr 1: 31.65 – 31.7 MbChr 4: 129.94 – 129.99 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Collagen alpha-1(XVI) chain is a protein that in humans is encoded by the COL16A1 gene.[5][6]

Function

This gene encodes the alpha chain of type XVI collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. High levels of type XVI collagen have been found in fibroblasts and keratinocytes, and in smooth muscle and amnion.[6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000084636 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000040690 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Pan TC, Zhang RZ, Mattei MG, Timpl R, Chu ML (Aug 1992). "Cloning and chromosomal location of human alpha 1(XVI) collagen". Proc Natl Acad Sci U S A. 89 (14): 6565–9. Bibcode:1992PNAS...89.6565P. doi:10.1073/pnas.89.14.6565. PMC 49542. PMID 1631157.
  6. 1 2 "Entrez Gene: COL16A1 collagen, type XVI, alpha 1".

Further reading


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