Cruze may refer to:
- Chevrolet Cruze, a compact car, and formerly a crossover SUV produced by General Motors.
- Chester Cruze, a former member of the Ohio House of Representatives
- James Cruze (1884–1942), silent film actor and film director
See also
- Rupert D'Cruze, British conductor
- Cruz
- Cruse (disambiguation)
- Cruise (disambiguation)
- Kruse (disambiguation)
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