De Filippo and its anglicised variant DeFilippo are surnames of Italian origin. People with those names include:
- Eduardo De Filippo (1900–1984), Italian actor, playwright, screenwriter, author and poet
- Gene DeFilippo (born c. 1952), American sports executive and former college athletics administrator
- John DeFilippo (born 1978), American football player and coach
- Luca De Filippo (1948–2015), Italian actor and director of theatre
- Luigi De Filippo (1930–2018), Italian actor, stage director and playwright
- Patrick DeFilippo (1939–2013), American mobster
- Peppino De Filippo (1903–1980), Italian actor
- Rebecca De Filippo (born 1994), Welsh rugby union player
- Titina De Filippo (1898–1963), Italian actress and playwright
- Vincent J. DeFilippo, master doll sculptor with Ideal Toy Company
- Vito De Filippo (born 1963), Italian politician
See also
- De Filippi, a surname
- All pages with titles containing De Filippo
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