Deadly Nightshade may refer to:
- Deadly nightshade (Atropa belladonna), a poisonous perennial herbaceous plant in the nightshade family
- Deadly Nightshade (comics), a Marvel Comics character
- Deadly Nightshade (film), a 1953 British crime drama film
- The Deadly Nightshade, an American rock and country band
- "Deadly Nightshade", a song by the Sword from the album Used Future
See also
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