Francisco de Aguirre (active 1646) was a Spanish painter, active in Toledo during the Baroque period. He was a pupil of Eugenio Caxes, and known chiefly as a portrait painter and a restorer of pictures in the cathedral.

References

• Bryan, Michael (1886). Robert Edmund Graves (ed.). Dictionary of Painters and Engravers, Biographical and Critical. Vol. I A-K. London: George Bell and Sons. p. 9.