Fred or Frederick Upton may refer to:
- George Frederick Upton, 3rd Viscount Templetown (1802–1890), Irish general and politician
- Frederick Upton (Whirlpool Corporation) (1890–1986), American corporate executive
- Fred Upton (born 1953), American politician; congressman from Michigan (grandson of above)
See also
- Fred Utton (1873–1939), Canadian sports shooter
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