CCDC88A
Identifiers
AliasesCCDC88A, APE, GIRDIN, GIV, GRDN, HkRP1, KIAA1212, coiled-coil domain containing 88A, PEHO, PEHOL
External IDsOMIM: 609736 MGI: 1925177 HomoloGene: 41180 GeneCards: CCDC88A
Orthologs
SpeciesHumanMouse
Entrez

55704

108686

Ensembl

ENSG00000115355

ENSMUSG00000032740

UniProt

Q3V6T2

Q5SNZ0

RefSeq (mRNA)

NM_001135597
NM_001254943
NM_018084
NM_001365480

NM_176841
NM_001363368
NM_001363369

RefSeq (protein)

NP_001129069
NP_001241872
NP_060554
NP_001352409

NP_789811
NP_001350297
NP_001350298

Location (UCSC)Chr 2: 55.29 – 55.42 MbChr 11: 29.32 – 29.46 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Girdin is a protein that in humans is encoded by the CCDC88A gene.[5][6][7] Although its cellular function are not fully elucidated, it has been associated with glioma.[8]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000115355 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032740 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Le-Niculescu H, Niesman I, Fischer T, DeVries L, Farquhar MG (Jun 2005). "Identification and characterization of GIV, a novel Galpha i/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles". J Biol Chem. 280 (23): 22012–20. doi:10.1074/jbc.M501833200. PMID 15749703.
  6. Anai M, Shojima N, Katagiri H, Ogihara T, Sakoda H, Onishi Y, Ono H, Fujishiro M, Fukushima Y, Horike N, Viana A, Kikuchi M, Noguchi N, Takahashi S, Takata K, Oka Y, Uchijima Y, Kurihara H, Asano T (May 2005). "A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis". J Biol Chem. 280 (18): 18525–35. doi:10.1074/jbc.M500586200. PMID 15753085.
  7. "Entrez Gene: KIAA1212 KIAA1212".
  8. Gu, F.; Wang, L.; He, J.; Liu, X.; Zhang, H.; Li, W.; Fu, L.; Ma, Y. (2014). "Girdin, an actin-binding protein, is critical for migration, adhesion, and invasion of human glioblastoma cells". Journal of Neurochemistry. 131 (4): 457–469. doi:10.1111/jnc.12831. PMID 25060559. S2CID 206090300.

Further reading


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