Julia A. Vorholt
2016
BornSeptember 15, 1969
Scientific career
ThesisFormylmethanofuran-Dehydrogenasen aus methanogenen Archaea Rolle von Eisen-Schwefel-Zentren, von Molybdän und Wolfram und von Selen (1997)
Doctoral advisorRudolf K. Thauer

Julia A. Vorholt (born September 15, 1969[1]) is a full professor of microbiology at ETH Zurich and an elected member of the German Academy of Sciences Leopoldina.[1]

Biography

She earned her PhD in 1997 under professor Rudolf K. Thauer at the Max Planck Institute for Terrestrial Microbiology, for which she was awarded the Otto Hahn Medal, and is a German national residing in Switzerland.[1] Following her Ph.D., she was a postdoctoral researcher with Mary Lidstrom at the University of Washington.[2]

She is a member of the European Academy of Microbiology (EAM).[3]

Research

Current projects of the Vorholt lab at ETH Zurich include:[4]

  • Phyllosphere microbiology: Characterizing and understanding standing microbial communities on above-ground plant surfaces, and their impact on plant health and productivity.
  • Metabolism of one-carbon compounds: The bacterial pathways that allow growth on single carbon compounds, especially methane and methanol.
  • Bacterial stress response: Pathways and regulation of mechanisms involved in bacterial stress response.
  • Single cell technologies: Development of microfluidics, in particular FluidFM, single cell force spectroscopy, and other techniques to gather data and manipulate individual cells.

In addition, work from her lab was significant in refuting previous claims by NASA scientists that the arsenic-tolerant bacteria GFAJ-1 could utilize arsenic instead of phosphorus in DNA and other essential biomolecules.[5][6]

Selected publications

As of 2013 she had 90 publications,[1] and as of 2015 her work has been cited approximately 4100 times.[7]

  • Chistoserdova L, Vorholt JA, Thauer RK, Lidstrom ME (1998). "C1 transfer enzymes and coenzymes linking methylotrophic bacteria and methanogenic Archaea". Science. 281 (5373): 99–102. doi:10.1126/science.281.5373.99. PMID 9651254.
  • Delmotte N, Knief C, Chaffron S, Innerebner G, Roschitzki B, et al. (2009). "Community proteogenomics reveals insights into the physiology of phyllosphere bacteria" (PDF). Proceedings of the National Academy of Sciences USA. 106 (38): 16428–16433. Bibcode:2009PNAS..10616428D. doi:10.1073/pnas.0905240106. PMC 2738620. PMID 19805315.
  • Vorholt, Julia A. (2012). "Microbial life in the phyllosphere". Nature Reviews Microbiology. 10 (12): 828–840. doi:10.1038/nrmicro2910. hdl:20.500.11850/59727. PMID 23154261. S2CID 10447146.
  • Elias M, Wellner A, Goldin-Azulay K, Chabriere E, Vorholt JA, Erb TJ, Tawfik DS (2012). "The molecular basis of phosphate discrimination in arsenate rich environments". Nature. 491 (7422): 134–137. Bibcode:2012Natur.491..134E. doi:10.1038/nature11517. PMID 23034649. S2CID 205230854.
  • Campagne S, Damberger FF, Kaczmarczyk A, Francez-Charlot A, Allain FH, Vorholt JA (2012). "Structural basis for sigma factor mimicry in the general stress response of Alphaproteobacteria". Proceedings of the National Academy of Sciences USA. 109 (21): E1405-14. doi:10.1073/pnas.1117003109. PMC 3361459. PMID 22550171.

References

  1. 1 2 3 4 Vorholt, Julia (August 2013). "Julia Vorholt CV" (PDF). Archived from the original (PDF) on 14 April 2015. Retrieved 14 April 2015.
  2. ↑ "Vorholt-Zambelli, Julia, Prof. Dr. | ETH Zurich". micro.biol.ethz.ch. Retrieved 2021-08-22.
  3. ↑ "Members".
  4. ↑ "Vorholt Lab Description". ETH Zurich. Archived from the original on 14 April 2015.
  5. ↑ Erb TJ, Kiefer P, Hattendorf B, Günther D, Vorholt JA (8 July 2012). "GFAJ-1 is an arsenate-resistant, phosphate-dependent organism". Science. 337 (6093): 467–70. Bibcode:2012Sci...337..467E. doi:10.1126/science.1218455. PMID 22773139. S2CID 20229329.
  6. ↑ Dan Vergano (July 9, 2012). "Discovery of an arsenic-friendly microbe refuted". USA Today.
  7. ↑ "Google Scholar Citation Index". Retrieved 1 April 2015.
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