KLF may refer to:
- The KLF, a band
- Karachi Literature Festival, held annually in Pakistan
- Kerala Literature Festival, held annually in India
- Kosmic Loader Foundation, later Kosmic Free Music Foundation, a netlabel
- Krüppel-like factors, proteins regulating gene expression
- Radio KLF, Finland
- Khalistan Liberation Force, Khalistani separatist militant organization
- Kaluga Airport IATA code
- Kunlun Fight, a Chinese kickboxing promotion
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