Kleiner (Hebrew: קליינר) is a German or Jewish surname, meaning "smaller":
- Alfred Kleiner, Swiss physicist
- Bruce Kleiner, American mathematician
- Krista Arrieta Kleiner, Filipino-American TV actress/singer and host
- Dick Kleiner, Hollywood columnist
- Eugene Kleiner, Silicon Valley venture capitalist
- Eugène-Louis Kleiner, Roman Catholic bishop
- Israel Kleiner (biochemist) (1885-1966), biochemist
- Israel Kleiner (mathematician), Canadian mathematician, professor at McGill University
- John J. Kleiner, US Congressman from Indiana
- Michael Kleiner, Israeli politician
- Morris Kleiner, American professor of public affairs
- Gastón Kleiner, Argentine musician
- Sergio Kleiner, Argentine soap opera star
- Yosef Kleiner, rabbi, psychologist, actor and intellectual
Fictional characters
- Isaac Kleiner, from the video games Half-Life and Half-Life 2.
Other meanings
- Kleiner Feldberg, mountain in Germany
- Kleiner Perkins Caufield & Byers, venture capital firm
- Kleiner Semmering Pass, mountain pass in Austria
- Kleiner Münsterländer, hunting-pointing-retrieving dog breed
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