Lagadapati is an Indian surname. Notable people with the surname include:
- Madhusudhan Rao Lagadapati (born 1966), businessman
- Lagadapati Rajagopal, Member of Parliament of India
- Lagadapati Sridhar, vice-chairman of Lanco Infratech
- Gopichand Lagadapati, actor, writer, director and producer
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