Lopresti is an Italian surname, also written LoPresti or Lo Presti. Notable people with the surname include:

• Aaron Lopresti (born 1964), an American comic book artist
• Charles LoPresti (born 1957), an American race horse trainer
• Danielle LoPresti (born 1969), American musician
• Matthew LoPresti, an American academic and politician
• Mike Lopresti (born 1953), an American sportswriter
• Jack Lopresti (born 1969), a British politician
• Jaime Lopresti (born 1974), a Chilean footballer
• Anna Banti (1895–1985), an Italian writer, art historian, critic, and translator, born Lucia Lopresti
• Pete LoPresti (born 1954), an American ice hockey player, son of Sam
• Peter Essex-Lopresti (1916–1951), a British orthopaedic surgeon
• Rodrigo Lopresti (born 1976), an American actor, director, and musician
• Rocco Lo Presti (1937–2009), an Italian mob boss of the Lo Presti 'ndrina
• Roy LoPresti (1929–2002), an American aeronautical engineer
• Sam LoPresti (1917–1984), an American ice hockey player, father of Pete
• Mike Lopresti (born 1981), Internet personality