MDV may refer to:
- Maldives, ISO 3166-1 alpha-3 country code
- MDV (TV station), Australian television station
- The IATA code for Omboué Hospital Airport
- The IOC code for Maldives Olympic Committee
- MDV Commercial Air Conditioner, Midea Group brand (active since 1999).
- Mitteldeutscher Verkehrsverbund (MDV), Transport and Tariff Association in the German Leipzig-Halle (Saale) area
- Michael de Vletter, high-profile member of the LSM Police Force
- Marek's disease virus
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