Macina may refer to:
- Macina Empire (1818–1862), former state located in present-day Mali
- Inner Niger Delta, also known as Macina, the floodplain area in Mali once controlled by the empire
- Macina, town and rural commune in Mali
- Macina (musical instrument), a high-pitched string instrument used in Indonesian kroncong music
See also
- Masina (disambiguation)
- Messina (disambiguation)
- Macinaggio, a French village in Corsica
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