Matron Stakes may refer to:

• Matron Stakes, the registered title of the Schweppervescence Trophy, a horse race held at Flemington Racecourse in Australia
• Matron Stakes (Ireland), a horse race held at Leopardstown Racecourse in Ireland
• Matron Stakes (NYRA), a New York Racing Association horse race currently held at Belmont Park, New York, in the United States
• Arlington Matron Stakes, a horse race held at Arlington Park, Illinois, in the United States
• Ontario Matron Stakes, a horse race held at Woodbine Park, Ontario, in Canada