Ojukwu is a family name of Nigerian origin, and may refer to:
- Bianca Odumegwu-Ojukwu (1968-) Nigerian politician, diplomat, lawyer, and businesswoman
- C. Odumegwu Ojukwu (1933–2011), aka Emeka Ojukwu, Nigerian military officer, statesman and politician
- Ernest Ojukwu (1960-), Nigerian professor of law
- John Ojukwu (born 1999), American football player
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