Patriarch Theophilus or Theophilos may refer to:

• Theophilus of Antioch, ruled in 169–182
• Theophilus I of Alexandria, ruled in 385–412
• Theophilus II (Coptic patriarch of Alexandria), reigned 952–956
• Theophilus II (Greek patriarch of Alexandria), reigned 1010–1020
• Theophilus III of Alexandria, Greek patriarch 1805–1825
• Theophilus I of Jerusalem, ruled in 1012–1020)
• Theophilus II of Jerusalem, Greek Orthodox Patriarch of Jerusalem, ruled 1417–1424
• Abuna Theophilos, second Patriarch of the Ethiopian Orthodox Tewahido Church, ruled in 1971–1976
• Patriarch Theophilos III of Jerusalem, ruled since 2005