Look up puffer in Wiktionary, the free dictionary.

Puffer may refer to:

• Clyde puffer, a type of cargo ship used in the Clyde estuary and off the west coast of Scotland
• Puffer, a type of circuit breaker
• Inhaler, a medical device used for delivering medication into the body via the lungs
• Puffer machine, used to detect explosives
• Puffer train, a class of patterns in automata such as Conway's Game of Life
• Pufferfish, a type of fish in family Tetraodontidae which can inflate itself as a defence mechanism
• Puffer (surname), a surname
• Supercharger for a motor car engine
• USS Puffer, two submarine vessels of the United States Navy
• Puffer, name for a particular type of German Wheellock pistol, usually from Nuremberg or Augsburg
• Puffer jacket, a type of jacket
• "Puffer", a song by indie rock/noise pop band Speedy Ortiz from Foil Deer
• Puffer (research study), online streaming service