| Ribosomal S10 leader | |
|---|---|
 Predicted secondary structure and sequence conservation of S10_leader. This picture was adapted from a previous publication. [1] | |
| Identifiers | |
| Symbol | S10 |
| Other data | |
| RNA type | Cis-reg; leader |
| Domain(s) | Bacteria |
| PDB structures | PDBe |
S10 ribosomal protein leader is a ribosomal protein leader involved in the ribosome biogenesis. It is used as an autoregulatory mechanism to control the concentration of the ribosomal protein S10. Known Examples were predicted in Clostridia[1] or other lineages of Bacillota[2] with bioinformatic approaches. The structure is located in the 5′ untranslated regions of mRNAs encoding ribosomal proteins S10 (rpsJ), L3 (rplc) and L4 (rplD).[1] There is an uncertainty about the ligand, because of a lack of experimental investigation.
See also
References
- 1 2 3 Eckert, I; Weinberg, Z (24 May 2020). "Discovery of 20 novel ribosomal leader candidates in bacteria and archaea". BMC Microbiology. 20 (130): 130. doi:10.1186/s12866-020-01823-6. PMC 7247131. PMID 32448158.
- ↑ Yao, Z; Barrick, J; Weinberg, Z; Neph, S; Breaker, R; Tompa, M; Ruzzo, WL (2007). "A computational pipeline for high-throughput discovery of cis-regulatory noncoding RNA in prokaryotes". PLOS Computational Biology. 3 (7): e126. Bibcode:2007PLSCB...3..126Y. doi:10.1371/journal.pcbi.0030126. PMC 1913097. PMID 17616982.
External links
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