| Ribosomal S6:S18 leader | |
|---|---|
 Predicted secondary structure and sequence conservation of S6:S18_leader. This picture was adapted from a previous publication. [1] | |
| Identifiers | |
| Symbol | S6:S18 |
| Other data | |
| RNA type | Cis-reg; leader |
| Domain(s) | Bacteria |
| PDB structures | PDBe |
S6:S18 ribosomal protein leader is a ribosomal protein leader involved in the ribosome biogenesis. It is used as an autoregulatory mechanism to control the concentration of the ribosomal proteins S6:S18 complex. An experimentally confirmed example of such a leader occurs in a wide variety of bacteria,[2] though not all phyla. A S6:S18 ribosomal leader was predicted in Chlorobia,[1] and its predicted structure differs from that of the validated S6:S18 ribosomal leader. This structure is located in the 5′ untranslated regions of mRNAs encoding ribosomal proteins rpsF (S6), the Single-strand DNA-binding protein A (ssbA), S18 (rpsR) and L7/L12 (rpll).[1]
See also
References
- 1 2 3 Eckert, I; Weinberg, Z (24 May 2020). "Discovery of 20 novel ribosomal leader candidates in bacteria and archaea". BMC Microbiology. 20 (130): 130. doi:10.1186/s12866-020-01823-6. PMC 7247131. PMID 32448158.
- ↑ Meyer, M (21 September 2018). "Ribosomal RNA Mimicry in RNA Regulation of Gene Expression". Microbiol. Spectr. 6 (2). doi:10.1128/9781683670247.ch7. S2CID 240183858.
External links
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