AKR7A2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesAKR7A2, AFAR, AFAR1, AFB1-AR1, AKR7, aldo-keto reductase family 7, member A2, aldo-keto reductase family 7 member A2
External IDsOMIM: 603418 MGI: 107796 HomoloGene: 2737 GeneCards: AKR7A2
Orthologs
SpeciesHumanMouse
Entrez

8574

110198

Ensembl

ENSG00000053371

ENSMUSG00000028743

UniProt

O43488

Q8CG76

RefSeq (mRNA)

NM_003689
NM_001320979

NM_025337

RefSeq (protein)

NP_001307908
NP_003680

NP_079613

Location (UCSC)Chr 1: 19.3 – 19.31 MbChr 4: 139.04 – 139.05 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Aflatoxin B1 aldehyde reductase member 2 is an enzyme that in humans is encoded by the AKR7A2 gene.[5][6]

Function

Aldo-keto reductases, such as AKR7A2, are involved in the detoxification of aldehydes and ketones.[supplied by OMIM][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000053371 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028743 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Ireland LS, Harrison DJ, Neal GE, Hayes JD (Aug 1998). "Molecular cloning, expression and catalytic activity of a human AKR7 member of the aldo-keto reductase superfamily: evidence that the major 2-carboxybenzaldehyde reductase from human liver is a homologue of rat aflatoxin B1-aldehyde reductase". Biochem J. 332 (1): 21–34. doi:10.1042/bj3320021. PMC 1219447. PMID 9576847.
  6. 1 2 "Entrez Gene: AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)".

Further reading


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