UNC is a three-letter abbreviation that may refer to:

Education

• University of North Carolina system in the United States
  • University of North Carolina at Chapel Hill, the flagship campus of the UNC system
    • North Carolina Tar Heels, the athletic program of the Chapel Hill campus
• University of Northern California (disambiguation), which may refer to:
  • University of Northern California (Santa Rosa) in Petaluma, California, United States
  • University of Northern California, Lorenzo Patiño School of Law, in Sacramento, California, United States
• University of Northern Colorado in Greeley, Colorado, United States
• Universidad Nacional de Córdoba in Córdoba, Argentina
• Universidad Nacional de Cajamarca, Spanish name of National University of Cajamarca
• Universitas Nicolai Copernici, Latin name of Nicolaus Copernicus University in Toruń, Poland
• Université de la Nouvelle-Calédonie (University of New Caledonia) in Nouméa, New Caledonia
• University of Nueva Caceres in Naga City, Camarines Sur, Philippines

Politics

• Cameroonian National Union (French: Union Nationale Camerounaise), a political party
• Union for the Congolese Nation (French: Union pour la nation congolaise), a political party in the Democratic Republic of the Congo
• United National Congress, a political party in Trinidad and Tobago
• United Nations Command, a multinational military force established to support the Republic of Korea (South Korea) during and after the Korean War
• Unlawful Non-Citizen, see Illegal immigration

Other

• Uncategorized, in reference to cyber threat groups as in UNC1151
• Uncirculated coin
• Unified coarse (or unified national coarse), a description of screw threads; see Unified Thread Standard
• Uniform Naming Convention, for Microsoft Windows systems
• Unguía Airport (IATA code: UNC) in Colombia
• United Nuclear Corporation, a nuclear mining, development, and applications company in operation from 1961 to 1997