William Matthews (April 26, 1755 – c. 1808) was an American politician. He was born in Cecil County, Maryland, and was a judge of the Cecil County Court in 1778, 1780, and 1782–1786. He was a member of the Maryland House of Delegates from 1786 to 1789.

He was later elected from the sixth district of Maryland as a Federalist to the Fifth Congress, serving from March 4, 1797, to March 3, 1799. In this position he was both preceded and succeeded by the Democratic-Republican Gabriel Christie. He is interred in his family's graveyard in Cecil County.

References

• United States Congress. "William Matthews (id: M000256)". Biographical Directory of the United States Congress.