Mixed doubles
2005 US Open
Champion	Daniela Hantuchová Mahesh Bhupathi
Runner-up	Katarina Srebotnik Nenad Zimonjić
Score	6–4, 6–2

Vera Zvonareva and Bob Bryan were the defending champions, but Zvonareva did not participate in this U.S. Open due to injury. Bryan partnered Rennae Stubbs, and the pair lost in the quarterfinals to Corina Morariu and Mike Bryan.

Daniela Hantuchová and Mahesh Bhupathi won the title, defeating Katarina Srebotnik and Nenad Zimonjić in the final 6–4, 6–2. With this win, Hantuchová completed the Career Grand Slam in Mixed Doubles, becoming the thirteenth player to complete this milestone.

Seeds

Draw

Finals

	Quarterfinals							Semifinals							Final
		Dinara Safina Andy Ram	6	6
		Samantha Stosur Paul Hanley	3	4
									Dinara Safina Andy Ram	1	5
									Katarina Srebotnik Nenad Zimonjić	6	7
		Katarina Srebotnik Nenad Zimonjić	7	5	[11]
	7	Martina Navratilova Leander Paes	62	7	[9]
																Katarina Srebotnik Nenad Zimonjić	4	2
																Daniela Hantuchová Mahesh Bhupathi	6	6
	5	Ai Sugiyama Kevin Ullyett	2	5
		Daniela Hantuchová Mahesh Bhupathi	6	7
									Daniela Hantuchová Mahesh Bhupathi	7	7
								6	Corina Morariu Mike Bryan	64	5
	6	Corina Morariu Mike Bryan	6	6
	2	Rennae Stubbs Bob Bryan	4	4

Section 1

	First round							Second round							Quarterfinals							Semifinals
	1	C Black W Black	67	6	[10]
	WC	A Frazier T Parrott	7	3	[8]				C Black W Black	3	4
		D Safina A Ram	6	6					D Safina A Ram	6	6
		J Husárová L Friedl	1	4												D Safina A Ram	6	6
		S Stosur P Hanley	7	6												S Stosur P Hanley	3	4
		M Kirilenko G Oliver	5	4					S Stosur P Hanley	7	6
		J Janković P Vízner	65	6	[6]			6	A Molik T Perry	61	4
	6	A Molik T Perry	7	2	[10]																		D Safina A Ram	1	5
	3	E Likhovtseva D Nestor	6	6																			K Srebotnik N Zimonjić	6	7
	WC	M Shaughnessy J Gimelstob	4	2				3	E Likhovtseva D Nestor	63	3
		K Srebotnik N Zimonjić	6	6					K Srebotnik N Zimonjić	7	6
		B Stewart J Erlich	4	2												K Srebotnik N Zimonjić	7	5	[11]
		V Ruano Pascuall S Huss	7	7											7	M Navratilova L Paes	62	7	[9]
	WC	L Osterloh K Kim	61	68					V Ruano Pascuall S Huss	1	4
		T Golovin F Santoro	3	2				7	M Navratilova L Paes	6	6
	7	M Navratilova L Paes	6	6

Section 2

	First round							Second round							Quarterfinals							Semifinals
	5	A Sugiyama K Ullyett	6	6
		ME "Ma.E" Salerni M Rodríguez	2	3				5	A Sugiyama K Ullyett	6	6
		A Medina Garrigues G Etlis	6	6					A Medina Garrigues G Etlis	3	4
	WC	L Granville R Leach	4	3											5	A Sugiyama K Ullyett	5	2
		Sun TT S Aspelin	6	3	[9]											D Hantuchová M Bhupathi	7	6
		D Hantuchová M Bhupathi	4	6	[11]				D Hantuchová M Bhupathi	6	7
	WC	S Perry A Delić	1	5				4	L Raymond J Björkman	3	62
	4	L Raymond J Björkman	6	7																			D Hantuchová M Bhupathi	7	7
	6	C Morariu M Bryan																				6	C Morariu M Bryan	64	5
	WC	J Craybas J Morrison						6	C Morariu M Bryan	2	6	[10]
		F Čermák AL Grönefeld	65	6	[10]				F Čermák AL Grönefeld	6	2	[7]
		K Peschke M Damm	7	4	[7]										6	C Morariu M Bryan	6	6
		N Pratt C Suk	1	6	[9]										2	R Stubbs B Bryan	4	4
		N Vaidišová M Knowles	6	1	[11]				N Vaidišová M Knowles	3	64
		T Garbin M Hood	2	1				2	R Stubbs B Bryan	6	7
	2	R Stubbs B Bryan	6	6

References

• Draw
• 2005 US Open – Doubles draws and results at the International Tennis Federation