Sentinel cells refer to cells in the body's first line of defense, which embed themselves in tissues such as skin.[1] Sentinel cells can refer to specific antigen-presenting cells, such as:
- Macrophages
- Kupffer cells - in the liver
- Langerhans cells - in the skin and mucosa (*these are a form of dendritic cells)
- Alveolar macrophages - in the lungs
- Microglia - in the brain
- Dendritic cells
Sentinel cells can also refer to cells that are normally not specialized antigen-presenting cells such as:[1]
- Mast cells
- Specialized T cells
Sometimes tissue cells not part of the immune system such as are also referred to as Sentinel cells:[1]
References
- 1 2 3 "sentinel cells". Retrieved November 13, 2013.
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