Singles
2021 Biella Challenger VII
Champion	Holger Rune
Runner-up	Marco Trungelliti
Score	6–3, 5–7, 7–6(7–5)

Thanasi Kokkinakis was the defending champion^[1] but chose not to defend his title.

Holger Rune won the title after defeating Marco Trungelliti 6–3, 5–7, 7–6^(7–5) in the final.

Seeds

Draw

Finals

	Semifinals							Final
		Felipe Meligeni Alves	3	6	3
		Marco Trungelliti	6	3	6
									Marco Trungelliti	3	7	65
								SE	Holger Rune	6	5	77
	SE	Holger Rune	7	2	6
		Tomás Martín Etcheverry	5	6	2

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	JP Varillas	6	6
		Z Kolář	3	1				1	JP Varillas	3	61
		R Olivo	6	6					R Olivo	6	77
		J Menezes	4	3												R Olivo	3	3
		R Marcora	3	1												F Meligeni Alves	6	6
		F Meligeni Alves	6	6					F Meligeni Alves	6	6
		A Collarini	5	6	4			7	M Kližan	2	4
	7	M Kližan	7	2	6																		F Meligeni Alves	3	6	3
	4	D Petrović	1	0r																			M Trungelliti	6	3	6
	Q	J Berrettini	6	2				Q	J Berrettini	5	6	6
		R Ramanathan	6	6					R Ramanathan	7	1	4
		B Kavčič	1	1											Q	J Berrettini	5	3
		M Trungelliti	6	6												M Trungelliti	7	6
	Q	H Grenier	0	2					M Trungelliti	6	6
	WC	L Nardi	6	4	1r			8	L Giustino	4	2
	8	L Giustino	2	6	4

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	5	F Ferreira Silva	6	7
		S Diez	3	5				5	F Ferreira Silva	6	63	2
		A Müller	6	6					A Müller	3	77	6
	WC	S Napolitano	4	1												A Müller	4	4
	SE	G Elias	1	6	6										SE	H Rune	6	6
	WC	F Cobolli	6	3	4			SE	G Elias	3	63
	SE	H Rune	6	64	77			SE	H Rune	6	77
	3	D Altmaier	2	77	65																	SE	H Rune	7	2	6
	6	K Żuk	6	6																			TM Etcheverry	5	6	2
	Q	R Brancaccio	4	2				6	K Żuk	7	7
		A Pellegrino	3	7	6				A Pellegrino	5	5
	Q	C Ugo Carabelli	6	5	1										6	K Żuk	4	3
		M Janvier	6	3	0											TM Etcheverry	6	6
		TM Etcheverry	4	6	6				TM Etcheverry	7	6
		L Lacko	2	3				2	N Milojević	5	3
	2	N Milojević	6	6

References

• Main draw
• Qualifying draw