Early

After graduating from the University of South Florida with a degree in theatre,^[9] Mandvi worked as a performer at Disney-MGM Studios at Walt Disney World Resort.^[4] He later moved to New York City, where he began appearing in off-Broadway productions. During this time, he was active in the band Cowboys and Indian. He won an Obie Award for his one-man show Sakina's Restaurant.^[10]

On Broadway, Mandvi appeared as Ali Hakim in the 2002 production of Oklahoma! directed by Trevor Nunn.^[11] He also appeared in the play Homebody/Kabul by Tony Kushner. He portrayed Fritz Haber in the off-Broadway play Einstein's Gift.

Mandvi played Melchior in On the Razzle by Tom Stoppard at the Williamstown Theatre Festival and appeared in the docudrama Guantanamo: Honor Bound to Defend Freedom at the Culture Project. In 2012 Mandvi starred in Disgraced at Lincoln Center's Claire Tow Theater. He played the lead role of Amir, a Pakistani- American lawyer struggling with his identity and Islam in the drama by Ayad Akhtar. The play won the 2013 Pulitzer Prize for Drama.^[12] Mandvi was nominated for a Lucille Lortel Award for his performance.^[13]

Television

Mandvi made his television debut as a doorman at the Miami Biltmore Hotel in the episode "Line of Fire" of the series Miami Vice. He has appeared in television shows including ER, The Sopranos, Sex and the City, CSI, Oz, Ed, The Bedford Diaries, Jericho, Sleeper Cell and various editions of Law & Order, including Criminal Intent, Special Victims Unit and Trial by Jury. He was the book reader for audio editions of Salman Rushdie's Shalimar the Clown (2005) and V. S. Naipaul's Magic Seeds (2004). In 2011 he appeared in Taco Bell commercials.

In 2006, Mandvi auditioned for The Daily Show. He was hired immediately and appeared on the show the same day.^[4] Mandvi became a regular correspondent in 2007. He often appears in segments satirizing and commenting on Islamic, Middle-Eastern, and South-Asian-related issues with such titles as "Senior Asian Correspondent," "Senior Middle East Correspondent," "Senior Foreign Looking Correspondent," and "Senior Muslim Correspondent."

In 2013, Mandvi was cast in a recurring role on the FOX romantic comedy, Us & Them.^[14]

In October 2013, during a segment on The Daily Show, Mandvi interviewed Don Yelton of the North Carolina Republican Party office. Comments he made then resulted in his resigning after the interview was aired.^[15]

Beginning in June 2015, Mandvi portrayed Rafiq Massoud in the HBO comedy series The Brink. In April 2015, Mandvi appeared on Person of Interest as Sulaiman Khan, the CEO of a software security firm. He was the lead actor, co-writer and producer of the web series Halal in the Family, which premiered on Funny or Die in 2015.

In 2016, Mandvi joined the climate change documentary show Years of Living Dangerously as one of its celebrity correspondents.^[16]

Beginning in 2017, Mandvi appeared in three episodes of the Netflix series A Series of Unfortunate Events as Montgomery "Uncle Monty" Montgomery,^[17] a herpetologist and distant relative of the Baudelaire children.

In 2019, Mandvi was cast in the Robert and Michelle King supernatural drama series Evil on CBS as Ben Shakir, a carpenter who works as a technical expert, equipment handler and debunker of supernatural phenomena.^[18][19]

Film

Mandvi played minor roles in the films The Siege and Die Hard with a Vengeance as well as the title role in Merchant Ivory Productions' film The Mystic Masseur. He had a major supporting role in the independent film American Chai, playing the lead character's roommate, "Engineering Sam." He played the doctor who diagnosed Paul Vitti's (Robert De Niro) panic attacks in Analyze This, and had a role as Mr. Aziz of "Joe's Pizza" in Spider-Man 2. He was also in commercials by Domino's Pizza and the Financial Industry Regulatory Authority (FINRA). He played the tone deaf doorman Khan in Music and Lyrics.

Mandvi at the 2010 San Francisco International Asian American Film Festival.

Mandvi played a dentist alongside Ricky Gervais in the 2008 romantic comedy Ghost Town, as well as office employee Bob Spaulding in The Proposal, starring Sandra Bullock. Today's Special, which Mandvi co-wrote with Jonathan Bines, premiered at the London Film Festival in October 2009 and New York's Mahindra Indo-American Arts Council Film Festival on November 11, 2009.^[20] He appeared in It's Kind of a Funny Story, a coming-of-age film written and directed by Anna Boden with Ryan Fleck, adapted from the 2006 novel by Ned Vizzini.^[21] He also co-starred as a Guantanamo captive in the film The Response, a script based on the transcripts of Combatant Status Review Tribunals convened in Guantanamo in 2004.^[22] In M. Night Shyamalan's The Last Airbender (released in 2010) he played a major role as Commander Zhao. Mandvi played the role of Mr. Chetty in the 2013 comedy The Internship and portrayed Ash Vasudevan in the 2014 film Million Dollar Arm.

Charity work and Advocacy

Mandvi is involved with disaster-relief organizations such as the charity initiative Relief 4 Pakistan, which assists in flood relief in Pakistan. In 2010, he hosted the "Stand Up for Religious Freedom" comedy event to raise money for the organization.^[29] After the 2010 Haiti earthquake, he performed with fellow Daily Show correspondent Wyatt Cenac at Conan O'Brien's "I'm with Coco" Benefit for earthquake victims. He is also a supporter of the Endometriosis Foundation of America.^[30][31][32]

In October 2023, Mandvi signed an open letter to Joe Biden, President of the United States, of artists calling for a ceasefire of the Israeli bombardment of Gaza.^[33]

Actor

Writer

Stage

Radio drama/podcast