Cefclidin
Names
IUPAC name
(6R,7R)-7-[[(2Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetyl]amino]-3-[(4-carbamoyl-1-azoniabicyclo[2.2.2]octan-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Other names
Antibiotic E 1040; Cefclidine; Cefaclidine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C21H26N8O6S2/c1-35-26-11(14-25-20(23)37-27-14)15(30)24-12-16(31)28-13(18(32)33)10(9-36-17(12)28)8-29-5-2-21(3-6-29,4-7-29)19(22)34/h12,17H,2-9H2,1H3,(H5-,22,23,24,25,27,30,32,33,34)/b26-11-/t12-,17-,21?,29?/m1/s1 ☒N
    Key: JUVHVMCKLDZLGN-TVNFHGJBSA-N ☒N
  • InChI=1/C21H26N8O6S2/c1-35-26-11(14-25-20(23)37-27-14)15(30)24-12-16(31)28-13(18(32)33)10(9-36-17(12)28)8-29-5-2-21(3-6-29,4-7-29)19(22)34/h12,17H,2-9H2,1H3,(H5-,22,23,24,25,27,30,32,33,34)/b26-11-/t12-,17-,21?,29?/m1/s1
    Key: JUVHVMCKLDZLGN-TVNFHGJBBE
  • O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)C(=N\OC)/c3nc(sn3)N)C[N+]45CCC(C(=O)N)(CC4)CC5)C([O-])=O
Properties
C21H26N8O6S2
Molar mass 550.61 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Cefclidin (also known as cefclidin, cefaclidine, or E1040) is a cephalosporin antibiotic.[1]

References

  1. ↑ Watanabe, N. A.; Katsu, K (1992). "Cefclidin (E1040), a novel cephalosporin: Lack of selection of beta-lactamase overproducing mutants in an in vitro pharmacokinetic model system". The Journal of Antibiotics. 45 (8): 1335–45. doi:10.7164/antibiotics.45.1335. PMID 1399855.


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