Chalicosis
Other namesFlint disease
SpecialtyRespirology

Chalicosis is a form of pneumoconiosis affecting the lungs or bronchioles, found mainly among stonecutters.[1] The disease is caused by the inhalation of fine particles of stone.[2] The term is from Greek, χάλιξ, gravel.

Risk factors

Occupations with significant exposure to stone dust are at an increased risk of chalicosis include:

Signs and symptoms

Signs and symptoms of chalicosis are slow to develop and thus patients may not show signs of incapacity until years after exposure.[7] It may even take up to 10 years before manifestations of the disorder are present.[8] Signs and symptoms include:

Treatment and Prevention

There is no definitive cure for chalicosis,[10] nor is there a specific targeted therapy.[3] Current treatment of this lung disorder primarily involves managing respiratory symptoms, associated comorbidities, and complications, with the overarching goal of enhancing the patient's quality of life.[10][11] These include:

Acute pharmacotherapies

  • Corticosteroids are a class of steroid hormones that can be used for acute management of chalicotic symptoms.[11][10]They are not recommended for chronic management.[11]

Chronic pharmacotherapies

  • Lung transplantation is a last resort in which one lung, both, or damaged lung tissue are replaced with a donor during a surgical procedure.[10]

References

  1. ↑ Betts, Wm. Winthrop (1900-01-13). "Chalicosis Pulmonum or Chronic Interstitial Pneumonia Induced by Stone Dust". JAMA: The Journal of the American Medical Association. XXXIV (2): 70. doi:10.1001/jama.1900.24610020006002a. ISSN 0098-7484.
  2. ↑ "The Free Medical Dictionary:chalicosis".
  3. 1 2 3 4 5 6 7 8 Chalicosis. (2018, November 19). In WikiDoc. https://www.wikidoc.org/index.php/Chalicosis
  4. 1 2 Betts, W. W. (1900). Chalicosis pulmonum or chronic interstitial pneumonia induced by stone dust. JAMA : the Journal of the American Medical Association, XXXIV(2), 70–74. https://doi.org/10.1001/jama.1900.24610020006002a
  5. 1 2 Møller, P. F. (1927). The radiographic picture in chalicosis, and its differential Diagnosis from other affections of the lungs. Acta Radiologica (Stockholm, Sweden : 1921), 8(3), 193–208. https://doi.org/10.3109/00016922709133740
  6. 1 2 3 Fine, M. J., & Jaso, J. V. (1935). Silicosis and primary carcinoma of the bronchus: Report of case. Journal of the American Medical Association, 104(1), 40–43. https://doi.org/10.1001/jama.1935.02760010042008
  7. 1 2 3 Fine, M. J., & Jaso, J. V. (1935). Silicosis and primary carcinoma of the bronchus: Report of case. Journal of the American Medical Association, 104(1), 40–43. https://doi.org/10.1001/jama.1935.02760010042008
  8. 1 2 3 4 Chalicosis. (2018, November 19). In WikiDoc. https://www.wikidoc.org/index.php/Chalicosis
  9. 1 2 3 4 5 Betts, W. W. (1900). Chalicosis pulmonum or chronic interstitial pneumonia induced by stone dust. JAMA : the Journal of the American Medical Association, XXXIV(2), 70–74. https://doi.org/10.1001/jama.1900.24610020006002a
  10. 1 2 3 4 5 6 7 8 Kerkar, P. (2014). Chalicosis or flint’s disease: Causes, symptoms, diagnosis, treatment, prevention. Epainassist - Useful Information for Better Health. https://www.epainassist.com/chest-pain/lungs/chalicosis-or-flints-disease
  11. 1 2 3 4 5 6 7 Chalicosis. (2018, November 19). In WikiDoc. https://www.wikidoc.org/index.php/Chalicosis


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