Ribosomal eL15 leader
Predicted secondary structure and sequence conservation of eL15_leader. This picture was adapted from a previous publication. [1]
Identifiers
SymboleL15
Other data
RNA typeCis-reg; leader
Domain(s)Archaea
PDB structuresPDBe

An eL15 ribosomal protein leader is a ribosomal protein leader involved in ribosome biogenesis. It is used as an autoregulatory mechanism to control the concentration of the ribosomal protein eL15, which is used in archaea and eukaryotes. Known Examples were predicted in Euryarchaeota with bioinformatic approaches.[1] The structure is located in the 5′ untranslated regions of mRNAs encoding ribosomal proteins eL15 (rpl15e).[1] Similarities between the eL15 ribosomal protein and the rRNA site to which this protein binds were detected.[1]

References

  1. 1 2 3 4 Eckert, I; Weinberg, Z (24 May 2020). "Discovery of 20 novel ribosomal leader candidates in bacteria and archaea". BMC Microbiology. 20 (130): 130. doi:10.1186/s12866-020-01823-6. PMC 7247131. PMID 32448158.
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