ENAH
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesENAH, ENA, MENA, NDPP1, enabled homolog (Drosophila), actin regulator
External IDsOMIM: 609061 MGI: 108360 HomoloGene: 134005 GeneCards: ENAH
Orthologs
SpeciesHumanMouse
Entrez

55740

13800

Ensembl

ENSG00000154380

ENSMUSG00000022995

UniProt

Q8N8S7

Q03173

RefSeq (mRNA)

NM_001008493
NM_018212

NM_001083120
NM_001083121
NM_008680
NM_010135

RefSeq (protein)

NP_001008493
NP_060682
NP_001364410
NP_001364411
NP_001364412

NP_001076589
NP_001076590
NP_032706
NP_034265

Location (UCSC)Chr 1: 225.49 – 225.65 MbChr 1: 181.72 – 181.85 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protein enabled homolog is a protein that in humans is encoded by the ENAH gene.[5][6]

Interactions

ENAH has been shown to interact with ABI1,[7] ZYX,[7][8] and PCARE.[9]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000154380 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022995 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Sazuka T, Tomooka Y, Kathju S, Ikawa Y, Noda M, Kumar S (October 1992). "Identification of a developmentally regulated gene in the mouse central nervous system which encodes a novel proline rich protein". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1132 (3): 240–248. doi:10.1016/0167-4781(92)90156-t. hdl:2027.42/29785. PMID 1420303.
  6. "Entrez Gene: ENAH enabled homolog (Drosophila)".
  7. 1 2 Tani K, Sato S, Sukezane T, Kojima H, Hirose H, Hanafusa H, Shishido T (June 2003). "Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinase". The Journal of Biological Chemistry. 278 (24): 21685–21692. doi:10.1074/jbc.M301447200. PMID 12672821.
  8. Drees B, Friederich E, Fradelizi J, Louvard D, Beckerle MC, Golsteyn RM (July 2000). "Characterization of the interaction between zyxin and members of the Ena/vasodilator-stimulated phosphoprotein family of proteins". The Journal of Biological Chemistry. 275 (29): 22503–22511. doi:10.1074/jbc.M001698200. PMID 10801818.
  9. Hwang T, Parker SS, Hill SM, Ilunga MW, Grant RA, Mouneimne G, Keating AE (December 2021). "A distributed residue network permits conformational binding specificity in a conserved family of actin remodelers". eLife. 10: e70601. doi:10.7554/eLife.70601. PMC 8639148. PMID 34854809.

Further reading

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.