Fredholm is a Swedish surname. Notable people with the surname include:
- Erik Ivar Fredholm (1866–1927), Swedish mathematician
- Fredholm alternative, in mathematics
- Fredholm determinant, in mathematics
- Fredholm integral equation, in mathematics
- Fredholm kernel, in mathematics
- Fredholm module, In noncommutative geometry
- Fredholm number, in number theory, apparently not in fact studied by Fredholm
- Fredholm operator, in mathematics
- Fredholm's theorem, in mathematics
- Analytic Fredholm theorem, in mathematics
- Fredholm theory, in mathematics
- Fredholm (crater), a small lunar impact crater
- 21659 Fredholm (1999 PR3), main-belt asteroid discovered in 1999 by P. G. Comba
- Ludwig Fredholm (1830–1891), Swedish industrialist
- Gert Fredholm (born 1941), Danish film director and screenwriter
- Patrik Fredholm (born 1978), Swedish footballer
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