GOLGA8A | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | GOLGA8A, GM88, golgin A8 family member A, GOLGA8B, CFAP286, FAP286 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 616180 HomoloGene: 121673 GeneCards: GOLGA8A | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Golgin A8 family member A is a protein that in humans is encoded by the GOLGA8A gene. [3]
Function
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked, flattened membrane sacs referred to as cisternae. Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. The golgins constitute a family of proteins which are localized to the Golgi. This gene encodes a golgin which structurally resembles its family member GOLGA2, suggesting that they may share a similar function. There are many similar copies of this gene on chromosome 15. Alternative splicing results in multiple transcript variants.
References
- 1 2 3 GRCh38: Ensembl release 89: ENSG00000175265 - Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Entrez Gene: Golgin A8 family member A". Retrieved 2017-05-31.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.