Hans-Peter Hauri | |
|---|---|
 Hans-Peter Hauri in 2008 | |
| Born | 13 February 1945 Zürich, Switzerland |
| Nationality | Swiss |
| Scientific career | |
| Fields | Biologist |
| Institutions | University of Zurich, University Hospital of Bern, Massachusetts General Hospital, Harvard University, Biozentrum, University of Basel |
Hans-Peter Hauri (born 13 February 1945 in Zürich) is a Swiss biologist[1]
Life
Hans-Peter Hauri, Professor emeritus of Cell Biology, conducted research at the Biozentrum of the University of Basel from 1983 to 2010. After completing biology studies at the University of Zurich followed by a doctoral thesis in 1973, he joined the Pediatric Clinic at the University Hospital of Bern. In 1978 he moved as a postdoc to the Massachusetts General Hospital and Harvard University, in Boston. In 1980 he returned to Switzerland and began research in Urs A. Meyer‘s Group, initially at the University of Zurich and later at the Biozentrum. Here he was appointed Associate Professor and in 2004 Professor of Cell Biology. In addition, he served as Director of Studies in Biology and Dean of the Faculty of Science at the University of Basel.
Work
Hans-Peter Hauri studied protein secretion, involving the movement of these proteins from the site of synthesis to their intended destination, during which the integrity of the cell organelles remained preserved.[2] Hauri discovered that the membrane protein CLIMP-63 mediates the interaction of the endoplasmic reticulum (ER) and microtubules.[3] In addition, he successfully established the ER-Golgi-intermediate compartment (ERGIC) as a cell organelle of the secretory pathway and could show that secretory proteins, produced in the ER, reach the Golgi apparatus via ERGIC.[4] Using a screening method, which he developed, he succeeded to systematically record protein interactions in the secretory pathway in living cells. Furthermore, he also elucidated the signaling networks of the secretory process.
References
- ↑ Prof. Dr. Hans-Peter Hauri, Emeritus. biozentrum.unibas.ch. Retrieved 2023-11-08
- ↑ Nyfeler, B; Hauri, H-P (2007-11-01). "Visualization of protein interactions inside the secretory pathway". Biochem Soc Trans. 35 (5): 970–3. PMID 17965257.
- ↑ Vedrenne, Cécile; Hauri, Hans-Peter (2006-06-07). "Morphogenesis of the endoplasmic reticulum: beyond active membrane expansion". Traffic. 6: 3507–14. PMID 16683914.
- ↑ Appenzeller-Herzog, Christian; Hauri, Hans-Peter (2006-06-01). "The ER-Golgi intermediate compartment (ERGIC): in search of its identity and function". J Cell Sci. 119 (1): 2173–83. PMID 16723730.