Prof Ilan Davis
Ilan Davis
Ilan Davis
Born1964
Known forRNA localization, advanced imaging
AwardsEMBO Member
Scientific career
FieldsCell Biology, Advanced Imaging
InstitutionsDepartment of Biochemistry, University of Oxford
ThesisIntracellular message localisation in Drosophila melanogaster (1990)
Doctoral advisorDavid Ish-Horowicz
Other academic advisorsPatrick H. O'Farrell
Websitewww.ilandavis.com
twitter.com/ilandavislab

Professor Ilan Davis[1] is a professor of Cell Biology and Wellcome Investigator at the Department of Biochemistry, University of Oxford. Previously (1996-2007) he was a Professor and Wellcome Trust Senior Fellow (2002-2007) at the Wellcome Trust Centre for Cell Biology, University of Edinburgh. In 2011, he was elected as an EMBO fellow.

Education

Davis studied Natural Sciences (Genetics) at King’s College, Cambridge, earning a BA in 1986. He then went on to complete a DPhil in Developmental Biology in 1990 under the supervision of David Ish-Horowicz at the Department of Zoology at University of Oxford. Davis completed postdoctoral research from 1992 to 1995 at the Department of Biochemistry and Biophysics, UCSF, in Patrick H. O'Farrell’s laboratory, with a Nato SERC postdoctoral fellowship followed by a Boyer postdoctoral Fellowship.

Research

His work focuses on the mechanism of mRNA transport [2] and localised translation [3] in the Drosophila nervous system.

Davis previously held, as the principal applicant, a Wellcome Career Development Fellowship, Lister Senior Fellowship (2000-2002), three Wellcome Trust Senior Research Fellowships (2002-2017), two Wellcome Trust Strategic Awards (2010-2021), MRC grant for Nanoscopy Oxford (2015-2020) and currently a Wellcome Investigator Award (2017-2023).

Selected publications

  • Gala, D. S., Titlow, J. S., Teodoro, R. O., & Davis, I. (2023). Far from home: the role of glial mRNA localization in synaptic plasticity. RNA, 29(2), 153-169.
  • Titlow, J. S., Kiourlappou, M., Palanca, A., Lee, J. Y., Gala, D. S., Ennis, D., ... & Davis, I. (2022). Systematic analysis of YFP gene traps reveals common discordance between mRNA and protein across the nervous system. bioRxiv, 2022-03.
  • Lee, J. Y., Wing, P. A., Gala, D. S., Noerenberg, M., Järvelin, A. I., Titlow, J., ... & Davis, I. (2022). Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences. Elife, 11, e74153.
  • Gala, D. S., Lee, J. Y., Kiourlappou, M. S., Titlow, J. S., Teodoro, R. O., & Davis, I. (2022). Mammalian glial protrusion transcriptomes predict localization of Drosophila glial transcripts required for synaptic plasticity. bioRxiv, 2022-11.
  • Wickenhagen, A., Sugrue, E., Lytras, S., Kuchi, S., Noerenberg, M., Turnbull, M. L., ... & Wilson, S. J. (2021). A prenylated dsRNA sensor protects against severe COVID-19. Science, 374(6567), eabj3624.

References

  1. ↑ "Prof Ilan Davis, Department of Biochemistry".
  2. ↑ Parton, RM; Hamilton, RS; Ball, G; Yang, L; Cullen, CF; Lu, W; Ohkura, H; Davis, I (2011). "A PAR-1–dependent orientation gradient of dynamic microtubules directs posterior cargo transport in the Drosophila oocyte". The Journal of Cell Biology. 194: 121–135. doi:10.1083/jcb.201103160. PMC 3135408. PMID 21746854.
  3. ↑ Weil, TT; Parton, RM; Herpers, B; Soetaert, J; Veenendaal, T; Xanthakis, D; Dobbie, IM; Halstead, JM; Hayashi, R; Rabouille, C; Davis, I (2012). "Drosophila patterning is established by differential association of mRNAs with P bodies". Nature Cell Biology. 14 (12): 1305–1315. doi:10.1038/ncb2627. PMC 4066581. PMID 23178881.
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