Karla Satchell
Born
Karla Fullner
EducationPacific Lutheran University (BA)
University of Washington (PhD)
AwardsInvestigator in Pathogenesis of Infectious Disease, Burroughs Wellcome Fund (2006)
Driskill Graduate Program Dean's Outstanding Teacher Award, Northwestern Feinberg School of Medicine (2016)
Scientific career
FieldsBacteriology
Structural biology
immunology
InstitutionsUniversity of Pittsburgh
Harvard Medical School
Northwestern University, Feinberg School of Medicine

Karla Satchell, born Karla Fullner, is an American microbiologist who is currently a professor at Northwestern University Feinberg School of Medicine[1] and an elected fellow of the American Association for the Advancement of Science.[2]

Education

She earned her Ph.D at University of Washington in 1996 and conducted postdoctoral training with John Mekalanos at Harvard Medical School.[1]

Research

Her interests are bacteriology, structural biology, and immunology,[3] cytoskeleton, cellular microbiology, bacteria and diseases[4] and pathogenesis.[1] She is especially known for defining how the MARTX toxin in Vibrio cholerae is a modular protein that delivers its constituent effectors to host cells.[5]

Immunology

Satchell is head of the Center for Structural Genomics of Infectious Diseases at Northwestern. The Center, established in 2007, provides an established consortium of laboratories in North America for rapid response research related to infectious disease outbreaks. It maps and examines the genomes of disease causing agents such as viruses to establish effective treatments.[6][7]

Publications

  • Kerri-Lynn Sheahan, Christina L. Cordero, and Karla J. Fullner Satchell. Identification of a domain within the multifunctional Vibrio cholerae RTX toxin that covalently cross-links actin. PNAS. vol. 101 no. 26. 9798–9803
  • KJF Satchell. MARTX, multifunctional autoprocessing repeats-in-toxin toxins. Infection and immunity. November 2007 vol. 75 no. 11 5079-5084.

Awards and honors

References

  1. 1 2 3 "Karla Satchell". northwestern.edu. Retrieved December 27, 2017.
  2. ↑ "Elected AAAS Fellows". northwestern.edu. December 13, 2016. Retrieved December 27, 2017.
  3. ↑ "Lab". satchell-lab.com. Retrieved December 27, 2017.
  4. ↑ "Karla Satchell". northwestern.edu. Retrieved December 27, 2017.
  5. ↑ Satchell, Karla J. F. (25 June 2015). "Multifunctional-autoprocessing repeats-in-toxin (MARTX) Toxins of Vibrios". Microbiology Spectrum. 3 (3). doi:10.1128/microbiolspec.VE-0002-2014. PMC 4509488. PMID 26185092.
  6. ↑ Rhodes, Dawn (January 24, 2020). "Northwestern University professor leading research team trying to stop coronavirus: 'We are here specifically for this.'". Chicago Tribune. Retrieved 2020-01-28.
  7. ↑ Scudellari, Megan (19 May 2020). "The sprint to solve coronavirus protein structures — and disarm them with drugs". Nature. Retrieved 2 November 2021.
  8. ↑ "Driskill Graduate Program Honors Students and Faculty". 12 September 2016.
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