Mitogen-activated protein kinase kinase kinase 15 is a protein that in humans is encoded by the MAP3K15 gene. [1]

Function

The protein encoded by this gene is a member of the mitogen-activated protein kinase (MAPK) family. These family members function in a protein kinase signal transduction cascade, where an activated MAPK kinase kinase (MAP3K) phosphorylates and activates a specific MAPK kinase (MAP2K), which then activates a specific MAPK. This MAP3K protein plays an essential role in apoptotic cell death triggered by cellular stresses.

References

  1. ↑ "Entrez Gene: Mitogen-activated protein kinase kinase kinase 15". Retrieved 2017-05-25.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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