MAPKAP1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMAPKAP1, JC310, MIP1, SIN1, SIN1b, SIN1g, mitogen-activated protein kinase associated protein 1, MAPK associated protein 1
External IDsOMIM: 610558 MGI: 2444554 HomoloGene: 11473 GeneCards: MAPKAP1
Orthologs
SpeciesHumanMouse
Entrez

79109

227743

Ensembl

ENSG00000119487

ENSMUSG00000038696

UniProt

Q9BPZ7

Q8BKH7

RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)Chr 9: 125.44 – 125.71 MbChr 2: 34.41 – 34.62 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Target of rapamycin complex 2 subunit MAPKAP1 is a protein that in humans is encoded by the MAPKAP1 gene.[5][6] As the name indicates, it is a subunit of mTOR complex 2.

This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene.[6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000119487 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000038696 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Schroder W, Cloonan N, Bushell G, Sculley T (Sep 2004). "Alternative polyadenylation and splicing of mRNAs transcribed from the human Sin1 gene". Gene. 339: 17–23. doi:10.1016/j.gene.2004.07.001. PMID 15363842.
  6. 1 2 "Entrez Gene: MAPKAP1 mitogen-activated protein kinase associated protein 1".

Further reading


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