MED9
Identifiers
Aliases	MED9, MED25, mediator complex subunit 9
External IDs	OMIM: 609878 MGI: 2183151 HomoloGene: 32385 GeneCards: MED9
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p11.2 Start 17,476,994 bp[1] End 17,493,221 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B1.3 Start 59,839,032 bp[2] End 59,853,031 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left ventricle gastrocnemius muscle nucleus accumbens caudate nucleus Brodmann area 9 prefrontal cortex putamen amygdala right lobe of liver right lobe of thyroid gland Top expressed in seminiferous tubule internal carotid artery yolk sac external carotid artery lens somite atrium dermis endocardial cushion brown adipose tissue More reference expression data BioGPS n/a
Gene ontology Molecular function transcription coregulator activity protein binding Cellular component mediator complex nucleus Biological process regulation of transcription by RNA polymerase II regulation of transcription, DNA-templated transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55090 192191 Ensembl ENSG00000141026 ENSMUSG00000061650 UniProt Q9NWA0 Q8VCS6 RefSeq (mRNA) NM_018019 NM_138675 RefSeq (protein) NP_060489 NP_619616 Location (UCSC) Chr 17: 17.48 – 17.49 Mb Chr 11: 59.84 – 59.85 Mb PubMed search [3] [4]
Wikidata
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Mediator complex subunit 9 (Med9) is a protein that in humans is encoded by the MED9 gene. ^[5]

Function

The multiprotein Mediator complex is a coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors. The protein encoded by this gene is thought to be a subunit of the Mediator complex. This gene is located within the Smith–Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008].

See also

• Mediator

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.