Markus Affolter
Markus Affolter (2015)
Born (1958-06-03) 3 June 1958
Seeberg BE
NationalitySwiss
Awards
Scientific career
FieldsDevelopmental Biologist
InstitutionsETH Zurich, Laval University, Biozentrum University of Basel

Markus Affolter (born 3 June 1958, in Seeberg BE)[1] is a Swiss Developmental Biologist and Professor at the Biozentrum University of Basel, Switzerland.

Life

Markus Affolter studied Biology at the ETH Zurich and at Laval University in Quebec City, Canada. Following his PhD from Laval University in 1988, he worked as a postdoctoral fellow at the Biozentrum, University of Basel. In the laboratory of Professor Walter Gehring, Markus Affolter began his research with the fruit fly Drosophila melanogaster. In 2000 he became Assistant Professor and in 2005 Professor of Developmental Biology at the Biozentrum, University of Basel.[2]

Work

Affolter researches the cellular and molecular processes involved in the formation of organs and blood vessel networks in the fruit fly Drosophila melanogaster and zebrafish. He has extensively used live-imaging, high-resolution microscopy in studying network formation in these animals, work which has enabled the better understanding of the function of molecules in morphogenesis. His lab has shown, in collaboration with the University of Freiburg, Germany and the University of Lausanne, that the morphogen Dpp and the feedback regulator Pentagone have key functions in proportional tissue growth (scaling) in the wing disc of the fruit fly.[3][4]

Awards and honors

References

  1. ↑ "Curriculum Vitae Prof. Dr. Markus Affolter" (PDF). leopoldina.org. Retrieved 2020-07-22.
  2. ↑ "Curriculum Vitae Markus Affolter". unibas.ch. Retrieved 2020-05-08.
  3. ↑ "Dpp Signaling Activity Requires Pentagone to Scale with Tissue Size in the Growing Drosophila Wing Imaginal Disc" https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1001182
  4. ↑ "Tracheal branching morphogenesis in Drosophila: New insights into cell behaviour and organ architecture". Retrieved 2020-05-08.
  5. ↑ K.M. Hunter Award National Cancer Institutes of Canada
  6. ↑ Affolter, M; Marty, T; Vigano, MA; Jaźwińska, A (2001). "Nuclear interpretation of Dpp signaling in Drosophila". EMBO J. 20 (13): 3298–305. doi:10.1093/emboj/20.13.3298. PMC 125521. PMID 11432817.
  7. ↑ National Academy of Sciences Leopoldina
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