| NEK9 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | NEK9, NERCC, NERCC1, Nek8, NIMA related kinase 9, APUG, LCCS10, NC | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 609798 MGI: 2387995 HomoloGene: 13222 GeneCards: NEK9 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Serine/threonine-protein kinase Nek9 is an enzyme that in humans is encoded by the NEK9 gene.[5][6]
Interactions
NEK9 has been shown to interact with:
References
- 1 2 3 GRCh38: Ensembl release 89: ENSG00000119638 - Ensembl, May 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000034290 - Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ Holland PM, Milne A, Garka K, Johnson RS, Willis C, Sims JE, Rauch CT, Bird TA, Virca GD (May 2002). "Purification, cloning, and characterization of Nek8, a novel NIMA-related kinase, and its candidate substrate Bicd2". The Journal of Biological Chemistry. 277 (18): 16229–40. doi:10.1074/jbc.M108662200. PMID 11864968.
- ↑ "Entrez Gene: NEK9 NIMA (never in mitosis gene a)- related kinase 9".
- ↑ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3: 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
- ↑ Belham C, Roig J, Caldwell JA, Aoyama Y, Kemp BE, Comb M, Avruch J (Sep 2003). "A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases". The Journal of Biological Chemistry. 278 (37): 34897–909. doi:10.1074/jbc.M303663200. PMID 12840024.
- 1 2 Roig J, Mikhailov A, Belham C, Avruch J (Jul 2002). "Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression". Genes & Development. 16 (13): 1640–58. doi:10.1101/gad.972202. PMC 186374. PMID 12101123.
- ↑ Tan BC, Lee SC (Mar 2004). "Nek9, a novel FACT-associated protein, modulates interphase progression". The Journal of Biological Chemistry. 279 (10): 9321–30. doi:10.1074/jbc.M311477200. PMID 14660563.
Further reading
- Pelka P, Scimè A, Mandalfino C, Joch M, Abdulla P, Whyte P (Jul 2007). "Adenovirus E1A proteins direct subcellular redistribution of Nek9, a NimA-related kinase". Journal of Cellular Physiology. 212 (1): 13–25. doi:10.1002/jcp.20983. PMID 17443675. S2CID 41137896.
- Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
- Wissing J, Jänsch L, Nimtz M, Dieterich G, Hornberger R, Kéri G, Wehland J, Daub H (Mar 2007). "Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry" (PDF). Molecular & Cellular Proteomics. 6 (3): 537–47. doi:10.1074/mcp.T600062-MCP200. PMID 17192257.
- Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- Bowers AJ, Boylan JF (Mar 2004). "Nek8, a NIMA family kinase member, is overexpressed in primary human breast tumors". Gene. 328: 135–42. doi:10.1016/j.gene.2003.12.002. PMID 15019993.
- Tan BC, Lee SC (Mar 2004). "Nek9, a novel FACT-associated protein, modulates interphase progression". The Journal of Biological Chemistry. 279 (10): 9321–30. doi:10.1074/jbc.M311477200. PMID 14660563.
- Belham C, Roig J, Caldwell JA, Aoyama Y, Kemp BE, Comb M, Avruch J (Sep 2003). "A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases". The Journal of Biological Chemistry. 278 (37): 34897–909. doi:10.1074/jbc.M303663200. PMID 12840024.
- Roig J, Mikhailov A, Belham C, Avruch J (Jul 2002). "Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression". Genes & Development. 16 (13): 1640–58. doi:10.1101/gad.972202. PMC 186374. PMID 12101123.
- Ohara O, Nagase T, Mitsui G, Kohga H, Kikuno R, Hiraoka S, Takahashi Y, Kitajima S, Saga Y, Koseki H (Apr 2002). "Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method". DNA Research. 9 (2): 47–57. doi:10.1093/dnares/9.2.47. PMID 12056414.
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