NUP85
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesNUP85, Nup75, FROUNT, nucleoporin 85, NPHS17
External IDsOMIM: 170285 MGI: 3046173 HomoloGene: 11755 GeneCards: NUP85
Orthologs
SpeciesHumanMouse
Entrez

79902

445007

Ensembl

ENSG00000125450

ENSMUSG00000020739

UniProt

Q9BW27

Q8R480

RefSeq (mRNA)

NM_001303276
NM_024844
NM_001330472

NM_001002929

RefSeq (protein)

NP_001290205
NP_001317401
NP_079120

NP_001002929

Location (UCSC)Chr 17: 75.21 – 75.24 MbChr 11: 115.46 – 115.47 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Nucleoporin 85 (Nup85) is a protein that in humans is encoded by the NUP85 gene.[5][6]

Function

Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP85 is part of one such subcomplex, Nup107-160.[6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000125450 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020739 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Doxsey SJ, Stein P, Evans L, Calarco PD, Kirschner M (Feb 1994). "Pericentrin, a highly conserved centrosome protein involved in microtubule organization". Cell. 76 (4): 639–50. doi:10.1016/0092-8674(94)90504-5. PMID 8124707. S2CID 20503793.
  6. 1 2 "Entrez Gene: NUP85 nucleoporin 85kDa".

Further reading


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.